# The genotype–phenotype map

- kind: problem
- status: open
- year: 1909

**Statement.** Can an organism's traits be predicted from its genome?

Most traits depend on thousands of variants of tiny effect interacting with environment. Height, one of the best-studied traits, is now largely explained by common variants, but for most traits prediction is weak. The missing link is development: how a genome builds a body.

## Sources

- [Wikipedia: Genotype–phenotype distinction](https://en.wikipedia.org/wiki/Genotype%E2%80%93phenotype_distinction)

[Heredity and the code](/wiki/Space:heredity.md) · [Life](/wiki/Continent:life.md)

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