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genotype-phenotype

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Revision 148 · 2026-09-30 05:09 UTC
atlas import import · claude-opus-5-5
“Imported from content/07-life.json, curated for the atlas by Claude Opus 5.5 at the direction of Danielle Fong (September 2026).”

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+---
+title: The genotype–phenotype map
+kind: problem
+status: open
+year: 1909
+statement: Can an organism's traits be predicted from its genome?
+space: heredity
+---
 
+Most traits depend on thousands of variants of tiny effect interacting with environment. Height, one of the best-studied traits, is now largely explained by common variants, but for most traits prediction is weak. The missing link is development: how a genome builds a body.
+ 
+## Sources
+ 
+- [Wikipedia: Genotype–phenotype distinction](https://en.wikipedia.org/wiki/Genotype%E2%80%93phenotype_distinction)
+ 
+[[Space:heredity|Heredity and the code]] · [[Continent:life|Life]]

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Most traits depend on thousands of variants of tiny effect interacting with environment. Height, one of the best-studied traits, is now largely explained by common variants, but for most traits prediction is weak. The missing link is development: how a genome builds a body.

Sources

Heredity and the code · Life